HMRI 2012 Publications

05 Jun HMRI 2012 Publications

In Vitro Systems/Tissue Engineering

Ingram M, Nakeff A, Techy G, Nolan JP, Imam SA and Ward BR. Tumor histoids: Scalable Synthesis of Realistic Human “Minitumor” for High Throughput Screening Poster Presented at the 27th Congress of the International Society for the Advancement of Cytometry in Lipzig, Germany, May 21-25, 2012.

Mehta G, Hsiao AY, Ingram M,  Luker GD and Takayama S. (2012). “Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.” J Control Release 164(2): 192-204.

Magnetic Resonance Spectroscopy

Lin AP1,2,3§, Bruno P4, Tran T2 ,Wen H3, Ross BD2. Age-Related Changes in Common Carotid artery Mean Wall Thickness and Cyclic Strain using MRI 1Biochemistry and Molecular Biophysics, California Institute of Technology, Pasadena, Ca, USA 2Huntington Medical Research Institutes, Pasadena, CA. USA 3National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 4University of California San Diego, La Jolla, CA, USA §Corresponding author.

Lin AP, Non-Invasive Imaging of Carotid Arterial Strain Using Displacement Encoded MRI Thesis In Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy, California Institute of Technology Pasadena, California 2009.

Manuscripts

Published

Zacharias NM, Chan HR, Sailasuta N, Ross BD, Bhattacharya P. Real-time molecular imaging of tricarboxylic acid cycle metabolism in Vivo by hyperpolarized 1-13C diethyl-succinate. Journal of The American Chemical Society (JACS). 2012; 134: 934-943. (NCT01463384).

Lin AP, Ross BD. Recent progress in clinical magnetic resonance spectroscopy. Encyclopedia of Magnetic Resonance (EMR). 2012; 1: 1-8.

Lin AP, Liao HJ, Merugumala SK, Prabhu SP, Meehan WP, Ross BD. Metabolic imaging of mild traumatic brain injury. Brain Imaging Behavior. 2012; 6:208-223.

Lingwood MD, Siaw TA, Sailasuta N, Abulseoud OA, Chan HR, Ross BD, Bhattacharya P, Han S. Hyperpolarized water as an MRI contrast agent: feasibility of In vivo imaging in a rat model. Radiology. Nov 2012; 265(2):418-425.

In Press

Cassidy, MC, Chan HR, Ross BD, Bhattacharya PK, Marcus CM. Supplementary information: In-vivo magnetic resonance imaging of hyperpolarized silicon particles. Nature. In Press 2012.

Submitted

Tran TT, Sailasuta N, Powell DK, Van Eldik LJ, Smith CD, Ross, BD. A standardized and reproducible protocol for proton magnetic resonance spectroscopy of human brain. Journal of Magnetic Resonance Imaging (JMRI). 2012.

Harris K, Tran T, Abulseoud O, Ross BD. Defining the impact of fasting on human brain acid-base homeostasis using natural abundance 13C and 31P MRS. Magnetic Resonance in Medicine. Sept 2012.

Lin A, Tran T, Bluml S, Merugumala S, Hui-jun L, Ross BD. Guidelines for acquiring and reporting clinical neurospectroscopy. Seminars in Neurology. Oct 2012.

Lin A, Ramadan S, Stern RA, Box H, Nowinski C, Ross BD, Mountford C. Changes in neurochemistry of athletes with repetitive head injury. Neuroimage. 2013.

Kanamori K and Ross BD.  Electrographic seizures are significantly reduced by in vivo inhibition of neuronal uptake of extracellular glutamine in rat hippocampus.  Journal of Neuroscience

Book Chapters Published

Kanamori K, Ross BD, Choi In-Young, Gruetter, Rold (Eds.). Nitrogen metabolism In Vivo, Chapter 35. (Neural Metabolism In Vivo4: Advances In Neurobiology). 2012; 1005-1026. Springer.

Submitted

Ross BD. Magnetic Resonance Spectroscopy for Neuroscientists and Clinicians: Hyperpolarized MR imaging and spectroscopy of the brain. Rothman & Stagg (Eds). 2012.

Abstracts Accepted

Tran T, Liu J,  Sailasuta N, Ross BD.  Is your brain really necessary: Combined quantitative MRI and quantitative MRS may improve early diagnosis of Alzheimer’s disease.  American Society of Neuroimaging. #P27. 2012.

Charleswell C, Tran T, Liu J, Sailasuta N, Ross BD. Prevention of Alzheimer’s disease through drug intervention: Design of quantitative biomarker monitoring. American Public Health Association. #271196. 2012.

Tran T, Liu J. Employing combined quantitative MRI and MRS markers to distinguish mild cognitive impairment. International Society for Magnetic Resonance in Medicine. #4442. 2012.

Submitted

Tran T, Liu J, Sailasuta J, Ross BD. Combined quantitative MRI and quantitative MRS may improve early diagnosis of Alzheimer’s disease. American Academy of Neurology. 2012.

Tran T, Ross BD. Smarter clinical design for drug discovery in MCI and AD. American Academy of Neurology. 2012.

Manuscript Submission Withheld

Lin, A, Ross BD, Tran T, Liu J, Shic F. Combining quantitative MRI with quantitative MRS for diagnosis of Alzheimer’s disease. (Withheld pending patent consideration)

Molecular Neurology

Arakaki X, McCleary P, Techy M, Kuo L, Fonteh AN, Armstrong B, Levy D, Harrington MG Na+, K+, ATPase isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat.  2012, Fluids and barriers of the CNS: under review.

Harrington MG, Schepkin V. Sodium MRI reveals in vivo protection from central sensitization by Na+, K+, ATPase inhibition  (Huntington Medical Research Institutes);  (FSU, NHMFL).  National High Magnetic field Laboratory 2012 Research Report

Schepkin VD, Harrington MG,  Changes in blood oxygenation in a rat migraine model (NHMFL/FSU, Tallahassee FL);  (Huntington Medical Research Institutes) National High Magnetic field Laboratory 2012 MagLab Research

Molecular Oncology

Schlussel A, Eggerding F, Donlon S, Gagliano, RA.  Analysis of the Adenomatous Polyposis Coli Variant: p.R414C.  Gary P. Wratten Annual Surgical Symposium, San Antonio, Texas, May 2012.

Jones LW, Coffee and Health in Thurston RW, et al, Coffee: A Handbook (2012), Lanham, MD. Roman & Littlefield.

Imaging Cancer TCA Cycle Metabolism By Hyperpolarized 13C Succinate In Vivo Bhattacharya, P.1*, Wagner, S.1, Perman, W.H.2, Epstein, A. L.3, Imam, A1, Zacharias, N.M.1, Ross, B1,4

Singer E, Linehan H, Babilonia G, Imam A, Smith D, Loera S, Wilson T, Smith S.  Stromal Response to Prostate Cancer: Nanotechnology-Based Detection of Thioredoxin-Interacting Protein artners Distinguishes Prostate Cancer Asscoiated Stroma from that of Benign Prostatic Hyperplasia   City of Hope, Huntington Medical Research Institute.

Liver

Lu, D. S., S. Siripongsakun, J. K. Lee, S. H. Wei, P. M. Cheng, S. Sabounchi, J. S. Lee, S. Raman, M. J. Tong, R. W. Busuttil and J. Sayre (2012). “Complete tumor encapsulation on MRI: A potentially useful imaging biomarker for better survival in solitary large hepatocellular carcinoma.” Liver Transpl.

Pan, C. Q., Z. P. Duan, K. R. Bhamidimarri, H. B. Zou, X. F. Liang, J. Li and M. J. Tong (2012). “An algorithm for risk assessment and intervention of mother to child transmission of hepatitis B virus.” Clin Gastroenterol Hepatol 10(5): 452-459.

Siripongsakun, S., J. K. Lee, S. S. Raman, M. J. Tong, J. Sayre and D. S. Lu (2012). “MRI detection of intratumoral fat in hepatocellular carcinoma: potential biomarker for a more favorable prognosis.” AJR Am J Roentgenol 199(5): 1018-1025.

Tong, M. J. (2012). “Improved understanding of risk factors could help to reduce the incidence of hepatocellular carcinoma.” Gastroenterol Hepatol (N Y) 8(5): 320-321.

Neural Engineering

Han M, Manoonkitiwongsa PS, Wang CX and McCreery DB. (2012). “In vivo validation of custom-designed silicon-based microelectrode arrays for long-term neural recording and stimulation.” IEEE Trans Biomed Eng 59(2): 346-354.

Yang Z, Liu W, Keshtkaran MR, Zhou Y, Xu J, Pikov V, Guan C and Lian Y. (2012). “A new EC-PC threshold estimation method for in vivo neural spike detection.” J Neural Eng 9(4): 046017.

McCreery D,  Han M,  Pikov V, Yadav K,  Pannu S. Encoding of the amplitude modulation of pulsatile electrical  stimulation in the feline cochlear nucleus by neurons in the inferior colliculus; Effects of stimulus pulse rate

(Submitted to Journal of Neural Engineering)

Electrical performance of penetrating microelectrodes chronically implanted in cat cortex Sheryl R. Kane, Member, IEEE, Stuart F. Cogan, Member, IEEE, Julia Ehrlich, Timothy D. Plante, Douglas B. McCreery, Member, IEEE, Philip R. Troyk, Senior Member IEEE,

(Submitted to IEEE transactions on Biomedical Engineering)

Romanenko S, Siegel PH, Wagenaar DA, Pikov V (2013) Comparison of the effects of millimeter wave irradiation, general bath heating, and localized heating on neuronal activity in the leech ganglion. (Submitted to International Journal of Optics and Photonics)

Rohan JG, Citron YR, Durrell AC, Cheruzel LE, Gray HB, Grubbs RH, Humayun M, Engisch KL, Pikov V, Chow RH (2013)  Light-triggered modulation of cellular electrical activity by ruthenium diimine nanoswitches. (Submitted to ACS Chemical Neuroscience)

Huntington Medical Research Institutes

Lu, D. S., S. Siripongsakun, J. K. Lee, S. H. Wei, P. M. Cheng, S. Sabounchi, J. S. Lee, S. Raman, M. J. Tong, R. W. Busuttil and J. Sayre (2012). “Complete tumor encapsulation on MRI: A potentially useful imaging biomarker for better survival in solitary large hepatocellular carcinoma.” Liver Transpl.

Pan, C. Q., Z. P. Duan, K. R. Bhamidimarri, H. B. Zou, X. F. Liang, J. Li and M. J. Tong (2012). “An algorithm for risk assessment and intervention of mother to child transmission of hepatitis B virus.” Clin Gastroenterol Hepatol 10(5): 452-459.

Siripongsakun, S., J. K. Lee, S. S. Raman, M. J. Tong, J. Sayre and D. S. Lu (2012). “MRI detection of intratumoral fat in hepatocellular carcinoma: potential biomarker for a more favorable prognosis.” AJR Am J Roentgenol 199(5): 1018-1025.

Tong, M. J. (2012). “Improved understanding of risk factors could help to reduce the incidence of hepatocellular carcinoma.” Gastroenterol Hepatol (N Y) 8(5): 320-321.