Title: Improved Long-term Survival with Remote Limb Ischemic Preconditioning in a Rat Fixed-Pressure Hemorrhagic Shock Model
Published: February 12, 2019
The article published in the journal Cardiovascular Drugs and Therapy was co-authored by HMRI’s Drs. Wandge Dai, Jianru Shi, Juan Carreno, Robert Kloner, and Sharon Hale. This is a very important paper as it shows for the first time that remote ischemic conditioning (a procedure where one simply inflates and deflates a blood pressure cuff on the limb) can markedly improve long-term survival from hemorrhagic shock (shock due to blood loss). It is the first of HMRI’s original papers from our U.S. Department of Defense (DOD) grant and could lead to novel therapies for wounded soldiers and civilians.