A HMRI preclinical study points to nicotine use near or at the time of a heart attack can further increase the size of the heart attack resulting in a more significant impact on recovery. Nicotine, a major component of tobacco smoke and also often added to e-liquid, has long been associated with high blood pressure and cardiac events. However, in this study HMRI’s Chief Science Officer Robert A. Kloner, MD, PhD, Neurosciences Science Director Michael Harrington MB, ChB, FRCP, and their team have uncovered that research subjects exposed to nicotine during or close to the time of their experimentally induced heart attack increased their blood pressure causing larger heart attacks that kill off more heart cells and further reduce the heart’s ability to pump.
Title: Acute administration of nicotine induces transient elevation of blood pressure and increases myocardial infarct size…
Date: November 16, 2020