HMRI’s migraine researchers explore new fundamental mechanisms to determine why and when migraine starts and develop new treatment strategies. This includes investigating sodium regulation and sex differences at the choroid plexus in migraine. Globally, migraine is among the top 2 leading causes of “years lived with disability.” The investigators are working on promising research that could lead to the alleviation of severe pain, disability, and disruptions to quality of life for those who suffer from migraines.