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The Analytical Biochemistry Lab (ABC) is an HMRI shared resource that supports investigators with sophisticated methodologies and detection systems for the identification, characterization, and quantification of compounds and their interactions. The ABC Lab is a well-equipped, comprehensive testing facility that features state-of-the-art instrumentation, including electrochemiluminescence platforms (MSD), chromatography systems, spectrophotometry analyzers, and sample preparation equipment to perform diverse techniques in biological and synthetic matrices. The Analytical Biochemistry Core provides collaborative services such as method development, optimization, and validation, in addition to complete testing services. Project management consultation is available to ensure objectives are met from experimental planning through implementation. 

The Analytical Biochemistry Lab operates on a charge back mechanism. All pricing is generated based on the cost of materials, labor, instrument time, and HMRI facilities/administration (F&A). Cost may vary based on the number of samples to be analyzed, as batching requirements impact personnel and instrument time. Method development and project management pricing is determined by the cost of labor and materials to support the defined scope of study. A final quote will be provided after the submission of an ABC request.

Instrumentation

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Thermo Scientific UHPLC/MS Vanquish Neo TSQ Altis Plus
The UHPLC/MS Vanquish Neo TSQ Altis is a state-of-the-art ultra high-performance liquid-chromatography mass-spectroscopy triple-quadrupole system used for sensitive, selective, precise, and reliable detection and quantitation of steroids, lipids, neurotransmitters, and novel disease biomarkers in complex biological matrices. 

Thermo Scientific Dionex ICS-6000 Ion Chromatography:
he ICS-6000 HPIC system is a top-of-the-line and high-performance ion chromatography system designed to address the full range of IC applications from trace-level analysis to high-performance simultaneous cation and anion quantitation.

Meso Scale Discovery (MSD) QuickPlex SQ 120 Electrochemiluminescence:
Meso Scale Discovery QuickPlex SQ 120 is a versatile electrochemiluminescence detection platform equipped to perform simultaneous highly sensitive analyses on a single sample for optimal efficiency. The MSD 120 is integral for cardiovascular, immunological, inflammatory, reproductive, intracellular signaling, proteomic, metabolic, neurobiological, oncological, and toxicological research through the quantitation of a wide range of potential biomarkers in various sample types.

Leadership

Mark Dixon
Chief Operation Officer

Natalie Astraea
Director of Laboratory Operations and Environmental Health & Safety 

Juan Carreno
Vivarium Director

Contact

Please reach out to lab.requests@hmri.org with inquiries.

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