EDUCATION IS A LIFELONG PURSUIT

Perhaps the best thing about science is its limitlessness. There is always more to explore. More questions to ask. More possibilities to test. More data to uncover. At HMRI, we are perpetual students. We hope you are too, and we challenge you to dive deeper with us.

Perhaps the best thing about science is its limitlessness. There is always more to explore. More questions to ask. More possibilities to test. More data to uncover. At HMRI, we are perpetual students. We hope you are too, and we challenge you to dive deeper with us.

POSTDOCTORAL FELLOWSHIP PROGRAM

We are thrilled to launch a formal postdoctoral fellowship program in 2021, thanks to a transformational grant we received from a generous supporter. With a mission of training and inspiring the next generation of independent researchers, HMRI will offer a handful of postdoctoral scientists an opportunity to perform cutting-edge research alongside our accomplished physician-scientists. In close collaboration with Caltech and the University of Southern California's Keck School of Medicine, fellows will advance their studies through innovative projects, new technologies, multi-disciplinary collaborations, networking opportunities and high-impact publications—all in our vibrant, state-of-the-art research facility here in the foothills of the San Gabriel Mountains in beautiful Pasadena.

POSTDOCTORAL FELLOWSHIP PROGRAM

We are thrilled to launch a formal postdoctoral fellowship program in 2021, thanks to a transformational grant we received from a generous supporter. With a mission of training and inspiring the next generation of independent researchers, HMRI will offer a handful of postdoctoral scientists an opportunity to perform cutting-edge research alongside our accomplished physician-scientists. In close collaboration with Caltech and the University of Southern California's Keck School of Medicine, fellows will advance their studies through innovative projects, new technologies, multi-disciplinary collaborations, networking opportunities and high-impact publications—all in our vibrant, state-of-the-art research facility here in the foothills of the San Gabriel Mountains in beautiful Pasadena.

We are seeking highly creative and enthusiastic candidates to investigate scientific questions surrounding widespread health concerns. If you are committed to exploring unknowns, developing breakthrough therapies and improving lives, you could be part of our inaugural postdoctoral fellowship program.

POST DOCTORAL FELLOWSHIP PROGRAM

Opportunities for investigative scientific research include:

  • Aging and Alzheimer's disease
  • Chronic migraines
  • Heart failure and heart attacks
  • Neuropsychiatric disease (mental illness)
  • Heart development
Applicants must select and apply for one of the following programs based on research interests, expertise and career trajectory:

Applicants must select and apply for one of the following programs based on research interests, expertise and career trajectory:

1) Aging and Alzheimer's disease (AD) Research (Scientific Director: Dr. Michael Harrington): The project will investigate new mechanisms underlying the early stages of neurodegeneration associated with aging and AD. New tests to predict or detect early AD will be designed. The ideal candidate will have a strong background in neuroscience or cell biology, with experience in cellular/subcellular fractionation, western blot, immunoassay, and chromatography/mass spectrometry techniques. An interest in neurodegeneration will be highly valued.

2) Migraine Research (Scientific Director: Dr. Michael Harrington): Migraine is among the top 5 leading causes of "years lived with disability". The project will explore new fundamental mechanisms as to why and when a migraine starts and develop new treatment strategies. Studies will be conducted in animal models and patients. The ideal candidate will have a strong background in neuroscience, and expertise in rodent behavioral models, cell culture, immunohistochemical labeling, and gene expression techniques will be preferred.

3) Cardiovascular Research (Chief Science Officer and Scientific Director: Dr. Robert Kloner): The project will investigate new mechanisms and models in heart failure and cardiogenic shock and generate novel approaches to reduce cell death during heart attack. New pharmacologic therapies that protect the mitochondria during ischemia/reperfusion are a recent focus of the laboratory. In addition, the acute and chronic effects of the now popular electronic cigarette smoke or vaping on the cardiovascular system in normal young versus old hearts, as well as hearts with underlying heart disease will be carefully examined. Furthermore, the effect of pure nicotine on the heart will be studied. Candidates with a background in vascular and myocardial biology will be preferred. Experience in molecular and cell biology techniques, biochemistry, bioinformatics, and murine cardiac models are all considered strengths for this position.

4) Neuropsychiatric Disease Research (Scientific Director: Dr. Anju Vasudevan): Dr. Vasudevan has relocated her laboratory from McLean Hospital/Harvard Medical School to HMRI (http://www.theabdl.org/). The project will investigate novel mechanisms underlying cell-autonomous programs that regulate endothelial and neuronal cell development in the forebrain, and uncover new causes for the origin of neuropsychiatric diseases like schizophrenia, autism, epilepsy and depression. The project will tap into the potential of CNS angiogenesis as a therapeutic source for recovery of neurological function in many diverse scenarios. The ideal candidate will have a relevant background either in neuroscience, developmental biology or cell biology with experience in endothelial cell culture, transgenic mouse models or stem cell biology.

5) Cardiovascular Research (Senior Research Scientist: Dr. Nicole Purcell): Dr. Purcell has relocated her laboratory from the University of California, San Diego to HMRI (https://profiles.ucsd.edu/nicole.purcell). The project will investigate a novel Ser/Thr phosphatase in the heart with age and following injury. In addition, the project will define the epigenetic mechanisms required for phosphatase mediated regulation of transcriptional changes that is important for cardiac homeostasis in young and aging mice. Using both in vitro and in vivo model systems we will determine novel targets that regulate cardiac growth and metabolic signaling with aging. The ideal candidate will have a strong background in molecular and cellular biology with expertise in primary cell culture, cardiac mouse models, biochemistry, bioinformatics, and myocardial biology.

Eligibility

Applicants must have completed a PhD, an MD, or an MD, PhD program and may have no more than five years of research training or experience since obtaining a doctoral-level degree.

Stipend and Resources

The initial appointment will be for two years with the possibility of extension. Salary is determined based on MD/PhD receipt date according to a set salary schedule, which begins at $54,080.00 up to a maximum of $59,000.00 plus benefits. Postdoctoral fellows will also receive up to $2,500 annually to support computing, travel and research needs.

Number of Years Average Annual Salary
Less than 1 year $54,080.00
1 year $54,500.00
2 years $56,000.00
3 years $57,500.00
4 years $59,000.00
Application and Process

Applications are accepted through http://bit.ly/HMRIpostdocapp.

Application materials should include a cover letter with a brief summary of career goals and objectives, CV, copies of published abstracts or papers and three letters of recommendation. Private letters of recommendation can be submitted using this form: http://bit.ly/postdocletter

Review of applications will begin immediately and continue until the positions are filled.

HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Undergraduate Summer Student Program

HMRI has a long history of hosting the Summer Student Program, providing undergraduate students with educational, hands-on experience in biomedical research. The program offers participants the opportunity to experience the day-to-day workings of a research facility and develop a better understanding of the scientific process. Each receives safety training before being assigned to a specific project by one of HMRI's researchers. At the end of the program, students give a presentation outlining their experience and research findings. Several of our Summer Student Program alumni have gone on to be chairs of medical school departments and medical research institutes! Sign up to receive program updates and additional information.

2021 Summer Student Program applications due March 31st!

Apply Now

This summer, current undergraduate, aspiring scientists will work alongside a science instructor and serve as teaching assistants for high school students enrolled in the summer STEM program. Participants will serve as mentors, insight into research methods and laboratory techniques. Our program offers a variety of scientific research opportunities, including Alzheimer's, migraine, traumatic brain injury, and cardiovascular laboratory-based research.

Undergraduate Summer Student Program

HMRI has a long history of hosting the Summer Student Program, providing undergraduate students with educational, hands-on experience in biomedical research. The program offers participants the opportunity to experience the day-to-day workings of a research facility and develop a better understanding of the scientific process. Each receives safety training before being assigned to a specific project by one of HMRI's researchers. At the end of the program, students give a presentation outlining their experience and research findings. Several of our Summer Student Program alumni have gone on to be chairs of medical school departments and medical research institutes! Sign up to receive program updates and additional information.

2021 Summer Student Program applications due March 31st!

Apply Now

This summer, current undergraduate, aspiring scientists will work alongside a science instructor and serve as teaching assistants for high school students enrolled in the summer STEM program. Participants will serve as mentors, insight into research methods and laboratory techniques. Our program offers a variety of scientific research opportunities, including Alzheimer's, migraine, traumatic brain injury, and cardiovascular laboratory-based research.

Eligibility:
  1. Applicants MUST be current undergraduate/graduate students enrolled in an academic program.
  2. Applicants MUST be over 18 years of age.
  3. If accepted into the program, students are required to attend and participate in the program which meets Monday-Friday, 9am-4pm in Pasadena, CA from June 17 to July 30.

Stipend and Resources: Selected students will receive a stipend amount.
The undergraduate students will also have the opportunity to participate in focused scientific discussions that will allow them to better understand the scientific process.

Application and Process:
 Application Link: https://hmriorg.wufoo.com/forms/p1xt0us003xgbc7/
  1. Applicant contact information
  2. Current school information
  3. Cover letter (upload)
  4. Resume (upload)
  5. List of three (3) references (upload)
  6. One (1) reference letter (upload)
  7. If your prof/employer prefers to submit the letter directly to HMRI they can do so by emailing it to HR@HMRI.ORG. In the meantime, upload a word or pdf document stating that they will be submitting the letter directly to HMRI. The application system will not allow you to submit your application unless a file is uploaded.
  8. Copy of college/university acceptance letter (upload)
  9. Copy of most recent school transcript (upload)
  10. Deadline to apply is March 31, 2021.

HIGH SCHOOL STEM PROGRAM

New in 2021, HMRI is thrilled to introduce Pasadena's first biomedical research High School STEM Program! Participants will explore a new topic each week, complete with hands-on lab activities and guidance from our passionate and accomplished scientific researchers. Our STEM program is open to juniors and seniors in the Pasadena Unified School District. We invite all budding scientists to apply! Please complete the online application, teacher recommendation and parent commitment forms before March 8, 2021.

HMRI Virtual STEM Program June 21-July 30, 2021
Join us as we explore new and uncharted solutions to some of healthcare's biggest challenges, like heart disease, Alzheimer's and mental illness.

Class in session daily 9am-2pm. All accepted students receive a paid stipend.

HIGH SCHOOL STEM PROGRAM

New in 2021, HMRI is thrilled to introduce Pasadena's first biomedical research High School STEM Program! Participants will explore a new topic each week, complete with hands-on lab activities and guidance from our passionate and accomplished scientific researchers. Our STEM program is open to juniors and seniors in the Pasadena Unified School District. We invite all budding scientists to apply! Please complete the online application, teacher recommendation and parent commitment forms before March 8, 2021.

HMRI Virtual STEM Program June 21-July 30, 2021
Join us as we explore new and uncharted solutions to some of healthcare's biggest challenges, like heart disease, Alzheimer's and mental illness.

Class in session daily 9am-2pm. All accepted students receive a paid stipend.

UNDERGRADUATE VOLUNTEER PROGRAM

HMRI's undergraduate volunteer program is a service that we at HMRI are providing for current undergraduate/graduate, aspiring scientists who would like to experience the research environment by working alongside top-level scientists at HMRI. Our students will gain insight into research through their volunteer time at HMRI and with HMRI collaborations. We maintain a variety of scientific disciplines at HMRI, some of which include research on Alzheimer's Disease, Migraine, Traumatic Brain Injury, and Cardiovascular signaling and laboratory-based research.

Accepting applications year-round. (Click here for the application) Our students will receive a high level of exposure to various laboratory techniques and will have the opportunity to participate in focused scientific discussions that will help guide our future research endeavors. This program is offered all year long, but we would prefer to select students who are willing to commit to HMRI research for at least a quarter/semester or up to 1 year which will give our volunteers extended knowledge in their respective fields of study. Students under good standing may continue in the lab longer with approval. Our student volunteer program is an exciting new approach at HMRI, where we concentrate our efforts on finding a good 'fit' for the students and their mentors in terms of domain expertise and motivation.

UNDERGRADUATE VOLUNTEER PROGRAM

HMRI's undergraduate volunteer program is a service that we at HMRI are providing for current undergraduate/graduate, aspiring scientists who would like to experience the research environment by working alongside top-level scientists at HMRI. Our students will gain insight into research through their volunteer time at HMRI and with HMRI collaborations. We maintain a variety of scientific disciplines at HMRI, some of which include research on Alzheimer's Disease, Migraine, Traumatic Brain Injury, and Cardiovascular signaling and laboratory-based research.

Accepting applications year-round. (Click here for the application) Our students will receive a high level of exposure to various laboratory techniques and will have the opportunity to participate in focused scientific discussions that will help guide our future research endeavors. This program is offered all year long, but we would prefer to select students who are willing to commit to HMRI research for at least a quarter/semester or up to 1 year which will give our volunteers extended knowledge in their respective fields of study. Students under good standing may continue in the lab longer with approval. Our student volunteer program is an exciting new approach at HMRI, where we concentrate our efforts on finding a good 'fit' for the students and their mentors in terms of domain expertise and motivation.

Eligibility:
  1. Applicants MUST be current undergraduate/graduate students enrolled in an academic program.
  2. Applicants MUST be over 18 years of age.
  3. We would prefer to select students who are willing to commit to HMRI research for at least a quarter/semester or up to 1 year.
Application and Process:
 Application Link:  https://hmriorg.wufoo.com/forms/x1empexn00qtez8/
  1. Applicant contact information
  2. Current school information
  3. Cover letter (upload)
  4. Resume (upload)
  5. List of three (3) references (upload)
  6. One (1) reference letter (upload)
  7. If your prof/employer prefers to submit the letter directly to HMRI they can do so by emailing it to HR@HMRI.ORG. In the meantime, upload a word or pdf document stating that they will be submitting the letter directly to HMRI. The application system will not allow you to submit your application unless a file is uploaded.
  8. Copy of college/university acceptance letter (upload)
  9. Copy of most recent school transcript (upload)

Fueling Dreams

Do you share our passion? Join us.

Give Now

Fueling Dreams.

Do you share our passion? Join us.

Give Now