February 18 at 4 pm | Oxidative Stress DrivesPHLPP1 Degradation through the Ubiquitin Proteasome Systemof the Heart

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Register for the Bob Mackin Lecture Series

FEBRUARY 18 | 4 pm

Via Zoom

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Khaja Shameem Mohammed Abdul, PhD

Postdoctoral Research Scholar, HMRI Cardiovascular Signaling Laboratory

Dr. Mohammed Abdul will present:

Oxidative Stress Drives PHLPP1 Degradation through the Ubiquitin Proteasome System of the Heart

ABOUT THE SPEAKER:

Khaja Shameem Mohammed Abdul, PhD, is a postdoctoral fellow in the Cardiovascular Signaling Laboratory at HMRI. Dr. Mohammed Abdul received his PhD from the University of Ruhuna, Sri Lanka, in 2017, where he worked on discovering viable noninvasive biomarkers for early detection of rare endemic chronic kidney disease of uncertain etiology (CKDu) in farming communities.

During his PhD work, he was awarded two distinguished scholarships, the Vice Chancellor’s Fellowship and the President’s Research Scholarship, from the University of Ruhuna and the Ministry of Higher Education (MOHE), Sri Lanka, respectively. During 2018-2020, as a post-doctoral fellow at Guangdong University of Technology, China, he investigated the molecular mechanisms of Isosteviol and its analog (JC105) in mediating cardioprotection against hypoxia-reoxygenation injury and myocardial injury models.

In 2021, Dr. Mohammed Abdul joined HMRI’s Postdoctoral Fellowship program. He investigates the role of protein phosphatases PHLPP1 and PHLPP2 in myocardial aging and injury, as well as the epigenetic alterations that regulate the transcription of genes involved in these processes. His long-term career goal is to become an independent career scientist in cardiovascular research. Apart from biomedical research, Dr. Mohammed Abdul enjoys playing cricket, nature photography, and horology.

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