Effects of Intracoronary SuperSaturated Oxygen Therapy on Myocardial Blood Flow, Microvascular Obstruction, and Myocardial Salva
Authors:
Journal: Journal of the American Heart Association
Publication Type: Journal Article
Date: 2025
DOI: PMC12449960
ID: 40673580
Abstract
Early reperfusion after ST-segment-elevation myocardial infarction is essential for limiting infarct size. However, reperfusion injury can lead to progressive microvascular obstruction (MVO), reducing myocardial blood flow (MBF), aggravating ischemia and myocardial necrosis. We hypothesized that SuperSaturated Oxygen (SSO) Therapy may reduce infarct size by alleviating MVO, so we evaluated the effects of SSO on the time course of MBF and MVO in a preclinical ischemia/reperfusion model.
Chemical List
- Oxygen
Reference List
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