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Recent Publications

  • Köhler TS, Kloner RA, Rosen RC, Burnett AL, Blaha MJ, Ganz P, Goldstein I, Kim NN, Lue T, McVary KT, Mulhall JP, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip ID, Miner M. The Princeton IV Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease. Mayo Clinic Proceedings. 2024 Aug 7:S0025-6196(24)00276-3.

  • Rosen RC, Miner M, Burnett AL, Blaha MJ, Ganz P, Goldstein I, Kim N, Kohler T, Lue T, McVary K, Mulhall J, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip I, Kloner RA. Proceedings of PRINCETON IV: PDE5 inhibitors and cardiac health symposium. Sexual Medicine Reviews. 2024 Jun 27:qeae043. 

  • Rezkalla SH, Kloner RA. An Urgent Call for Studies That Address the Cardiovascular Consequences of Legalization of Marijuana. Cardiology Research Journal. 2024 Apr;15(2):86-89.

  • Kloner RA, Stanek E, Desai K, Crowe CL, Paige Ball K, Haynes A, Rosen RC. The association of tadalafil exposure with lower rates of major adverse cardiovascular events and mortality in a general population of men with erectile dysfunction. Clinical Cardiology Journal. 2024 Feb; 47(2):e24234.

  • Dai W, Shi J, Siddarth P, Carreno J, Kleinman MT, Herman DA, Arechavala RJ, Renusch S, Hasen I, Ting A, Kloner RA. Effects of Electronic Cigarette Vaping on Cardiac and Vascular Function, and Post-myocardial Infarction Remodeling in Rats. Cardiovascular Toxicology. 2024 Feb;24(2):199-208. 

  • Corradetti G, Oncel D, Kadomoto S, Arakaki X, Kloner RA, Sadun AA, Sadda SR, Chan JW. Choriocapillaris and Retinal Vascular Alterations in Presymptomatic Alzheimer's Disease. Investigative Ophthalmology and Visual Science. 2024 Jan 2;65(1):47.

  • Kloner RA, Burnett AL, Miner M, Blaha MJ, Ganz P, Goldstein I, Kim NN, Kohler T, Lue T, McVary KT, Mulhall JP, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip ID, Rosen RC. Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health. The Journal of Sexual Medicine. 2024 Jan 30;21(2):90-116. 

  • Sachdeva J, Karunananthan A, Shi J, Dai W, Kleinman MT, Herman D, Kloner RA. Flavoring Agents in E-cigarette Liquids: A Comprehensive Analysis of Multiple Health Risks. Cureus. 2023 Nov 18;15(11):e48995. 

  • Shavelle DM, Bosson N, French WJ, Thomas JL, Niemann JT, Gausche-Hill M, Rollman JE, Rafique AM, Klomhaus AM, Kloner RA. Association of the COVID-19 Pandemic on Treatment Times for ST-Elevation Myocardial Infarction: Observations from the Los Angeles County Regional System. The American Journal of Cardiology. 2024 Feb 15;213:93-98.

Historic Publications

Frequently cited historical papers from Dr. Kloner and his colleagues

  • Braunwald E, Kloner RA. The stunned myocardium: Prolonged, postischemic ventricular dysfunction. Circulation 1982; 66(6): 1146-1149. (4099 citations). 

  • Kloner RA, Ganote CE, Jennings RB. The “no-reflow” phenomenon after temporary coronary occlusion in the dog. The Journal of Clinical Investigation 1974; 54(6): 1496-1508. (2551 citations).

  • Gottleib RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. The Journal of Clinical Investigation 1994; 94(4): 1621-1628 (2128 citations).

  • Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P. Regional ischemic preconditioning protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 1993; 87(3): 893-899 (1940 citations). 

  • Kloner RA, Shook T, Przyklenk K, Davis VG, Junio L, Matthews RV, Burstein S, Gibson M, Poole WK, Cannon CP et al. Previous angina alters in-hospital outcomes in TIMI 4. A clinical Correlate to preconditioning? Circulation 1995; 91 (1): 37-45. (796 citations). 

  • Kloner RA, Bolli R, Marban E, Reinlib L, Braunwald E. Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop. Circulation 1998; 97 (18): 1848-1867. (771 citations). 

  • Leor J, Poole WK, Kloner RA. Sudden cardiac death triggered by an earthquake. New England Journal of Medicine 1996; 334 (7): 413-419. (1103 citations).

  • Kloner RA, Rude RE, Carlson N, Maroko PR, DeBoer LW, Braunwald E. Ultrastructural evidence of microvascular damage and myocardial cell injury after coronary artery occlusion: which comes first? Circulation 1980: 62 (5): 945-952 (656 citations). 

  • Dai W, Hale SL, Martin BJ, Kuang JQ, Dow JS, Wold LE, Kloner RA. Allogenic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short-and long-term effects. Circulation 2005; 112 (2): 214-223 (801 citations).  

  • Braunwald E, Kloner RA. Myocardial reperfusion: a double-edged sword? The Journal of Clinical Investigation 1985: 76(5): 1713-1719. (1849 citations). 

  • Birnbaum Y, Hale SL, Kloner RA. Ischemic preconditioning at a distance: reduction of myocardial infarct size by partial reduction of blood supply combined with rapid stimulation of the gastrocnemius muscle in the rabbit. Circulation 1997; 96(5): 1641-1646. (579 citations). 

  • Kloner RA. Forman MB, Gibbons RJ, Ross AM, Alexander RW, Stone GW. Impact of time to therapy and reperfusion modality on the efficacy of adenosine in acute myocardial infarction: the AMISTAD-2 trial. European Heart Journal 2006; 27(20); 2400-2405. (320 citations). 

  • Przyklenk K, Kloner RA. Superoxide dismutase plus catalase improve contractile function in the canine model of the “Stunned myocardium.” Circulation Research 1986; 58 (1): 148-156 (472 citations). 

  • Kloner RA. Current state of clinical translation of cardioprotective agents for acute myocardial infarction. Circulation Research 2013; 113(4): 451-463. (185 citations). 

  • Kloner RA, Stanek E, Crowe CL, Singhal M, Pepe RS, Bradsher J, Rosen RC. Effect of phosphodiesterase type 5 inhibitors on major adverse cardiovascular events and overall mortality in a large nationwide cohort of men with erectile dysfunction and cardiovascular risk factors. A retrospective, observational study based on healthcare claims and national death index. The Journal of Sexual Medicine 2023; 20(1): 38-48.  (21 citations).
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