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Type 2 diabetes and later cognitive function in older American Indians: The Strong Heart Study.

Authors: Brenna Cholerton|||Adam Omidpanah|||Steven P Verney|||Lonnie A Nelson|||Laura D Baker|||Astrid Suchy-Dicey|||William T Longstreth|||Barbara V Howard|||Jeffrey A Henderson|||Thomas J Montine|||Dedra Buchwald

Journal: International journal of geriatric psychiatry

Publication Type: Journal Article

Date: 2019

DOI: NIHMS1022171

ID: 30924200

Affiliations:

Affiliations

    Department of Pathology, Stanford University, Palo Alto, CA, USA.|||Department of Community Health, Washington State University, Seattle, WA, USA.|||Department of Psychology, University of New Mexico, Albuquerque, NM, USA.|||Department of Community Health, Washington State University, Seattle, WA, USA.|||Department of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.|||Department of Community Health, Washington State University, Seattle, WA, USA.|||Department of Neurology, School of Medicine University of Washington, Seattle, WA, USA.|||MedStar Health Research Institute, Hyattsville, MD, USA.|||Black Hills Center for American Indian Health, Rapid City, SD, USA.|||Department of Pathology, Stanford University, Palo Alto, CA, USA.|||Department of Community Health, Washington State University, Seattle, WA, USA.

Abstract

Insulin resistance is a substantial health issue for American Indians, with type 2 diabetes overrepresented in this population as compared with non-Hispanic whites. Insulin resistance and its related conditions in turn increase risk for dementia and cognitive impairment. The aim of the current study was to determine whether type 2 diabetes and insulin resistance at midlife was associated with later-life cognitive testing in a large sample of older American Indians, aged 65 and older.


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