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Body Mass Index, White Matter Hyperintensities, and Cognitive Performance in American Indians: Data from the Strong Heart Study.

Authors: Anna Zamora-Kapoor|||Luciana Hebert|||Lonnie Nelson|||Dean Shibata|||W T Longstreth|||Barbara V Howard|||Dedra Buchwald|||Astrid Suchy-Dicey

Journal: Journal of racial and ethnic health disparities

Publication Type: Journal Article

Date: 2023

DOI: NIHMS1874703

ID: 36223053

Affiliations:

Affiliations

    Department of Medical Education and Clinical Sciences, Institute for Research and Education to Advance Community Health, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA. anna.zamora-kapoor@wsu.edu.|||Department of Medical Education and Clinical Sciences, Institute for Research and Education to Advance Community Health, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA.|||College of Nursing, Washington State University, Spokane, WA, USA.|||University of Washington, Seattle, WA, USA.|||University of Washington, Seattle, WA, USA.|||MedStar Health Research Institute, Hyattsville, MD, USA.|||Department of Medical Education and Clinical Sciences, Institute for Research and Education to Advance Community Health, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA.|||Department of Medical Education and Clinical Sciences, Institute for Research and Education to Advance Community Health, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA.

Abstract

Previous studies report that obesity can be a risk and a protective factor for cognitive health. However, they have not examined whether white matter hyperintensities (WMH) mediate the association between mid- or late-life body mass index (BMI) and late-life cognitive performance. We examined this question in American Indians, a population underrepresented in neuropsychological research.


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