Executive function changes before memory in preclinical Alzheimer's pathology: a prospective, cross-sectional, case control stud
Authors:
Journal: PloS one
Publication Type: Journal Article
Date: 2013
DOI: PMC3832547
ID: 24260210
Abstract
Early treatment of Alzheimer's disease may reduce its devastating effects. By focusing research on asymptomatic individuals with Alzheimer's disease pathology (the preclinical stage), earlier indicators of disease may be discovered. Decreasing cerebrospinal fluid beta-amyloid42 is the first indicator of preclinical disorder, but it is not known which pathology causes the first clinical effects. Our hypothesis is that neuropsychological changes within the normal range will help to predict preclinical disease and locate early pathology.
Chemical List
- Amyloid beta-Peptides
Reference List
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