Cardiovascular Research

Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation

Authors: Emanuela Castigli|||Stephen A Wilson|||Abdallah Elkhal|||Esra Ozcan|||Lilit Garibyan|||Raif S Geha

Affiliations: + Expand

Abstract

Transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) is a receptor used by B cell-activating factor of the TNF family and a proliferation-inducing ligand (APRIL) to induce isotype switching independently of CD40 and is mutated in patients with common variable immunodeficiency.

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Chemical List

CD40 Antigens|||Interferon Regulatory Factors|||Tnfrsf13b protein, mouse|||Tnfsf13 protein, mouse|||Transmembrane Activator and CAML Interactor Protein|||Tumor Necrosis Factor Ligand Superfamily Member 13|||interferon regulatory factor-4|||Interleukin-4|||Immunoglobulin E|||AICDA (Activation-Induced Cytidine Deaminase)|||Cytidine Deaminase

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Reference List

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