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  • Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, ElKhal A. NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat Commun. 2014 Oct 7;5:5101.
     
  • Oberhuber R, Heinbokel T, Cetina Biefer HR, Boenisch O, Hock K, Bronson RT, Wilhelm MJ, Iwakura Y, Edtinger K, Uehara H, Quante M, Voskuil F, Krenzien F, Slegtenhorst B, Abdi R, Pratschke J, Elkhal A, Tullius SG. CD11c+ Dendritic Cells Accelerate the Rejection of Older Cardiac Transplants via Interleukin-17A. Circulation. 2015 Jul 14;132(2):122-31. doi: 10.1161/CIRCULATIONAHA.114.014917. Epub 2015 May 8.

  •  Elkhal A, Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Quante M, Seyda M, Schuitenmaker JM, Krenzien F, Camacho V, de la Fuente MA, Ghiran I, Tullius SG. NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent. Sci Rep. 2016 Mar 1;6:22325. doi: 10.1038/srep22325.

  •  Uehara M, McGrath MM, Ohori S, Solhjou Z, Banouni N, Routray S, Evans C, DiNitto JP, Elkhal A, Turka LA, Strom TB, Tullius SG, Winkler DG, Azzi J, Abdi R. Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ. Nat Commun. 2017 Oct 16;8(1):951.

  • Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, Koduru S, El Fatimy R, Ghiran I, Trachtenberg AJ, de la Fuente MA, Azuma H, Akbari O, Tullius SG, Vasudevan A, Elkhal A. Mast cells regulate CD4+?T-cell differentiation in the absence of antigen presentation. J Allergy Clin Immunol. 2018 Dec;142(6):1894-1908.e7. 

  • El Fatimy R, Li S, Chen Z, Mushannen T, Gongala S, Wei Z, Balu DT, Rabinovsky R, Cantlon A, Elkhal A, Selkoe DJ, Sonntag KC, Walsh DM, Krichevsky AM. MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways. Acta Neuropathol. 2018 Oct;136(4):537-555. 

  • Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A. Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Res. 2018 Feb;28(2):221-248. doi: 10.1038/cr.2017.135. Epub 2017 Oct 31.

  • Biefer HRC, Elkhal A, Cesarovic N, Emmert MY. NAD+ the disregarded molecule in cardiac metabolism. Eur Heart J. 2020 Mar 1;41(9):983-986. doi: 10.1093/eurheartj/ehaa044. 

  • Iske J, Seyda M, Heinbokel T, Maenosono R, Minami K, Nian Y, Quante M, Falk CS, Azuma H, Martin F, Passos JF, Niemann CU, Tchkonia T, Kirkland JL, Elkhal A, Tullius SG. Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation. Nat Commun. 2020 Aug 27;11(1):4289.

  •  Subburaju S, Kaye S, Choi YK, Baruah J, Datta D, Ren J, Kumar AS, Szabo G, Fukumura D, Jain RK, Elkhal A, Vasudevan A. NAD+-mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior. Sci Adv. 2020 Oct 9;6(41):eabb9766. 

  • Datta D, Subburaju S, Kaye S, Baruah J, Choi YK, Nian Y, Khalili JS, Chung S, Elkhal A, Vasudevan A. Human forebrain endothelial cell therapy for psychiatric disorders. Mol Psychiatry. 2021 Sep;26(9):4864-4883. Epub 2020 Jul 13. 

  • Jasper Iske, Rachid El Fatimy, Yeqi Nian, Amina Ghouzlani, Siawosh K. Eskandari, Hector Rodriguez Cetina Biefer, Anju Vasudevan, and Abdallah Elkhal. NAD+ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages. eLife. 2024 Feb 19.
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