Cardiovascular Research

Histologic signatures of thermal injury: applications in transmyocardial laser revascularization and radiofrequency ablation.

Authors: P Whittaker|||S Zheng|||M J Patterson|||R A Kloner|||K E Daly|||R A Hartman

Affiliations: + Expand

Abstract

Cardiac treatments such as transmyocardial laser revascularization and radiofrequency ablation cause thermal injury. We sought to provide quantitative histologic methods of assessing such injury by using the inherent birefringence of cardiac muscle and collagen; specifically, to exploit the connection between thermal injury and the loss of birefringence.

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Chemical List

Collagen