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Myocardial infarction temporally related to ephedra--a possible role for the coronary microcirculation.

Authors: Shereif H Rezkalla|||Juan Mesa|||Param Sharma|||Robert A Kloner

Journal: WMJ : official publication of the State Medical Society of Wisconsin

Publication Type: Case Reports

Date: 2002

ID: 12426924

Affiliations:

Affiliations

    Department of Cardiology, Marshfield Clinic, 1000 N Oak Ave, Marshfield, WI 54449, USA. rezkalls@mfldclin.edu|||||||||

Abstract

Myocardial infarction has been reported with ephedrine and pseudoephedrine use. It has been suggested that these agents may induce coronary artery spasm, hypercoagulable states, or oxygen demand imbalance. We report a 25-year-old male with myocardial infarction after receiving a diet pill containing ephedra. Coronary angiography revealed normal coronary arteries with very slow flow, suggestive of microcirculation abnormalities. The flow responded promptly to intracoronary verapamil.