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Transplantation of neonatal cardiomyocytes after permanent coronary artery occlusion increases regional blood flow of infarcted

Authors: Thorsten Reffelmann|||Joan S Dow|||Wangde Dai|||Sharon L Hale|||Boris Z Simkhovich|||Robert A Kloner

Journal: Journal of molecular and cellular cardiology

Publication Type: Journal Article

Date: 2003

DOI: 10.1016/s0022-2828(03)00081-6

ID: 12788378

Affiliations:

Affiliations

    The Heart Institute, Good Samaritan Hospital, University of Southern California, 1225 Wilshire Boulevard, CA 90017-2395, Los Angeles, USA|||||||||||||||

Abstract

Cellular cardiomyoplasty is a promising approach for rebuilding scar tissue after acute myocardial infarction. However, the angiogenic potential of transplanted immature cardiomyocytes and their effect on regional myocardial blood flow (RMBF) after coronary artery occlusion remain to be evaluated.