Cardiovascular Research

Hypothermia during reperfusion limits 'no-reflow' injury in a rabbit model of acute myocardial infarction.

Authors: Sharon L Hale|||Michael W Dae|||Robert A Kloner

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Abstract

Reflow following coronary artery occlusion is an important predictor of clinical outcome. This study tests the effects of regional hypothermia, initiated late during ischemia and maintained for 2 h of reperfusion, on the no-reflow phenomenon.