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Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects.

Authors: Wangde Dai|||Sharon L Hale|||Bradley J Martin|||Jin-Qiang Kuang|||Joan S Dow|||Loren E Wold|||Robert A Kloner

Journal: Circulation

Publication Type: Journal Article

Date: 2005

DOI: 10.1161/CIRCULATIONAHA.104.527937

ID: 15998673

Affiliations:

Affiliations

    The Heart Institute, Good Samaritan Hospital, Division of Cardiovascular Medicine of Keck School of Medicine at University of Southern California, Los Angeles, CalifA 90017, USA.||||||||||||||||||

Abstract

Mesenchymal stem cells (MSCs) have the potential to replace infarct scar, but the long-term effects are unknown. We studied short- and long-term effects of MSC transplantation on left ventricular (LV) function in a rat myocardial infarction model.