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Ischemic preconditioning for the clinician.

Authors: Shereif H Rezkalla|||Robert A Kloner

Journal: WMJ : official publication of the State Medical Society of Wisconsin

Publication Type: Journal Article

Date: 2006

ID: 16878655

Affiliations:

Affiliations

    Department of Cardiology, Marshfield Clinic, Marshfield, Wisconsin 54449, USA. rezkalla.shereif@marshfieldclinic.org|||

Abstract

Ischemic preconditioning is a physiologic phenomenon that occurs in the cardiac muscle in which brief episodes of ischemia protect the heart when exposed to a sustained ischemia. Clinical counterparts include potential benefits of preinfarction angina and less ischemia after a second, compared to a first, coronary angioplasty balloon inflation. This article will discuss how preconditioning might be applied to the clinical setting during acute myocardial infarction, coronary interventions, and cardiac surgery.