Cardiovascular Research

Delayed treatment with hypothermia protects against the no-reflow phenomenon despite failure to reduce infarct size.

Authors: Sharon L Hale|||Michael J Herring|||Robert A Kloner

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Abstract

Many studies have shown that when hypothermia is started after coronary artery reperfusion (CAR), it is ineffective at reducing necrosis. However, some suggest that hypothermia may preferentially reduce no-reflow. Our aim was to test the effects of hypothermia on no-reflow when initiated close to reperfusion and 30 minutes after reperfusion, times not associated with a protective effect on myocardial infarct size.

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Reference List

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