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Improved myocardial perfusion after transmyocardial laser revascularization in a patient with microvascular coronary artery dise

Authors: Peyman Mesbah Oskui|||Guy S Mayeda|||Steven Burstein|||Ali Gheissari|||William J French|||Joseph Thomas|||Robert A Kloner

Journal: SAGE open medical case reports

Publication Type: Case Reports

Date: 2014

DOI: PMC4857340

ID: 27489642

Affiliations:

Affiliations

    Department of Cardiology, Harbor-UCLA Medical Center, Torrance, CA, USA; Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA.|||Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA; Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.|||Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA; Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.|||Department of Cardiothoracic Surgery, Good Samaritan Hospital, Los Angeles, CA, USA.|||Department of Cardiology, Harbor-UCLA Medical Center, Torrance, CA, USA.|||Department of Cardiology, Harbor-UCLA Medical Center, Torrance, CA, USA.|||Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA; Department of Cardiology, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA.

Abstract

We report the case of a 59-year-old woman who presented with symptoms of angina that was refractory to medical management. Although her cardiac catheterization revealed microvascular coronary artery disease, her symptoms were refractory to optimal medical management that included ranolazine. After undergoing transmyocardial revascularization, her myocardial ischemia completely resolved and her symptoms dramatically improved. This case suggests that combination of ranolazine and transmyocardial revascularization can be applied to patients with microvascular coronary artery disease.


Reference List

    Allen KB, Dowling RD, Fudge TL, et al. Comparison of transmyocardial revascularization with medical therapy in patients with refractory angina. N Engl J Med 1999; 341: 1029–1036.|||Schofield PM, Sharples LD, Caine N, et al. Transmyocardial laser revascularization in patients with refractory angina: a randomized controlled trial. Lancet 1999; 353: 519–524.|||Burkhoff D, Schmidt S, Schulman SP, et al. Transmyocardial laser revascularization compared with continued medical therapy for treatment of refractory angina pectoris: a prospective randomized trial. Lancet 1999; 354: 885–890.|||Jones JW, Schmidt SE, Richman BW, et al. Holmium:YAG laser transmyocardial revascularization relieves angina and improves functional status. Ann Thorac Surg 1999; 67: 1596–1602.|||Leon MB. DIRECT (DMR In Regeneration of Endomyocardial Channels Trial). Presented at Late-Breaking Trials, Transcatheter Cardiovascular Therapeutics, Washington, DC, 19 October 2000.|||Stone GW, Teirstein PS, Rubenstein R, et al. A prospective, multicenter, randomized trial of percutaneous transmyocardial laser revascularization in patients with nonrecanalizable chronic total occlusions. J Am Coll Cardiol 2002; 39(10): 1581–1587.|||Gassler N, Wintzer HO, Stubbe HM, et al. Transmyocardial laser revascularization: histological features in human nonresponder myocardium. Circulation 1997; 95: 371–375.|||Kwong KF, Kanellopoulos GK, Nickols JC, et al. Transmyocardial laser treatment denervates canine myocardium. J Thorac Cardiovasc Surg 1997; 114: 883–890.|||Hirsch GM, Thompson GW, Arora RC, et al. Transmyocardial laser revascularization does not denervate the canine heart. Ann Thorac Surg 1999; 68: 460–468.|||Hardy RI, Bove KE, James FW, et al. A histologic study of laser-induced transmyocardial channels. Lasers Surg Med 1987; 6: 563–573.|||Cheng D, Diegeler A, Allen K, et al. Transmyocardial laser resvascularization: a meta-analysis and systemic review of controlled trials. Innovations 2006; 1: 295–313.