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Improved Long-term Survival with Remote Limb Ischemic Preconditioning in a Rat Fixed-Pressure Hemorrhagic Shock Model.

Authors: Wangde Dai|||Jianru Shi|||Juan Carreno|||Sharon L Hale|||Robert A Kloner

Journal: Cardiovascular drugs and therapy

Publication Type: Journal Article

Date: 2019

DOI: 10.1007/s10557-019-06860-6

ID: 30747397

Affiliations:

Affiliations

    HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, 686 S. Fair Oaks Ave., Pasadena, CA, 91105, USA. Wangdedai@yahoo.com.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, 686 S. Fair Oaks Ave., Pasadena, CA, 91105, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, 686 S. Fair Oaks Ave., Pasadena, CA, 91105, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, 686 S. Fair Oaks Ave., Pasadena, CA, 91105, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, 686 S. Fair Oaks Ave., Pasadena, CA, 91105, USA.

Abstract

We investigated whether bilateral, lower limb remote ischemic preconditioning (RIPC) improved long-term survival using a rat model of hemorrhagic shock/resuscitation.


Chemical List

    Biomarkers|||Carrier Proteins|||Crp protein, rat|||Cytokines