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Different Effects of Volatile and Nonvolatile Anesthetic Agents on Long-Term Survival in an Experimental Model of Hemorrhagic Sh

Authors: Wangde Dai|||Jianru Shi|||Juan Carreno|||Robert A Kloner

Journal: Journal of cardiovascular pharmacology and therapeutics

Publication Type: Comparative Study

Date: 2020

DOI: 10.1177/1074248420919221

ID: 32292050

Affiliations:

Affiliations

    HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, Pasadena, CA, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, Pasadena, CA, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, Pasadena, CA, USA.|||HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, Pasadena, CA, USA.

Abstract

We investigated whether the cardioprotective, volatile gas anesthetic agent, isoflurane, could improve survival and organ function from hemorrhagic shock in an experimental rat model, compared to standard nonvolatile anesthetic agent ketamine/xylazine.

Chemical List

    Anesthetics, Dissociative|||Anesthetics, Inhalation|||Ketamine|||Isoflurane