Impact of electronic cigarette vaping on the cardiovascular function in young and old rats.
Authors:
Journal: Scientific reports
Publication Type: Journal Article
Date: 2024
DOI: PMC11621403
ID: 39639066
Abstract
While the acute exposure to electronic cigarette (E-cig) vapor has been associated with an increase in blood pressure, the chronic effect of E-cig vapor on blood pressure compared to standard cigarette smoke has not been extensively studied. We determined the effect of E-cig exposure on blood pressure and other measures of cardiac function in both young and old rats.
Chemical List
- Nicotine
Reference List
- Moriyama, C. et al. Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines. Am. J. Respir Cell. Mol. Biol.42 (3), 304–311 (2010).|||Gould, N. S. et al. Aging adversely affects the cigarette smoke-induced glutathione adaptive response in the lung. Am. J. Respir Crit. Care Med.182 (9), 1114–1122 (2010).|||Zhou, S., Wright, J. L., Liu, J., Sin, D. D. & Churg, A. Aging does not enhance experimental cigarette smoke-induced COPD in the mouse. PLoS One. 8 (8), e71410 (2013).|||Bandi, P. et al. Changes in E-Cigarette Use among U.S. adults, 2019–2021. Am. J. Prev. Med.65 (2), 322–326 (2023).|||Rose, J. J. et al. Cardiopulmonary impact of electronic cigarettes and Vaping products: A Scientific Statement from the American Heart Association. Circulation148 (8), 703–728 (2023).|||Dai, W. et al. Effects of electronic cigarette exposure on myocardial infarction and No-Reflow, and cardiac function in a rat model. J. Cardiovasc. Pharmacol. Ther.28, 10742484231155992. 10.1177/10742484231155992 (2023 Jan-Dec).|||Osborn, J. W. Jr, Barber, B. J., Quillen, E. W. Jr, Abram, R. J. & Cowley, A. W. Jr. Chronic measurement of cardiac output in unanesthetized rats using miniature thermocouples. Am. J. Physiol.251 (6 Pt 2), H1365–H1372 (1986).|||Machin, D. R. et al. Ultrasound Assessment of Flow-mediated dilation of the Brachial and superficial femoral arteries in rats. J. Vis. Exp. ;(117):54762. (2016).|||Cheng, K. S., Baker, C. R., Hamilton, G., Hoeks, A. P. & Seifalian, A. M. Arterial elastic properties and cardiovascular risk/event. Eur. J. Vasc Endovasc Surg.24 (5), 383–397 (2002).|||Flammer, A. J. et al. The assessment of endothelial function: from research into clinical practice. Circulation126 (6), 753–767 (2012).|||Celermajer, D. S. et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation88 (5 Pt 1), 2149–2155 (1993).|||Celermajer, D. S. et al. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl. J. Med.334 (3), 150–154 (1996).|||Carnevale, R. et al. Acute Impact of Tobacco vs Electronic cigarette smoking on oxidative stress and vascular function. Chest150 (3), 606–612 (2016).|||Rao, P., Liu, J. & Springer, M. L. JUUL and Combusted cigarettes comparably impair endothelial function. Tob. Regul. Sci.6 (1), 30–37 (2020).|||Daiber, A., Kuntic, M., Oelze, M., Hahad, O. & Münzel, T. E-cigarette effects on vascular function in animals and humans. Pflugers Arch.475 (7), 783–796 (2023).|||Middlekauff, H. R., Park, J. & Moheimani, R. S. Adverse effects of cigarette and noncigarette smoke exposure on the autonomic nervous system: mechanisms and implications for cardiovascular risk. J. Am. Coll. Cardiol.64 (16), 1740–1750 (2014).|||Benowitz, N. L. & Fraiman, J. B. Cardiovascular effects of electronic cigarettes. Nat. Rev. Cardiol.14 (8), 447–456 (2017).|||Martinez-Morata, I., Sanchez, T. R., Shimbo, D. & Navas-Acien, A. Electronic cigarette use and blood pressure endpoints: a systematic review. Curr. Hypertens. Rep.23 (1), 2. 10.1007/s11906-020-01119-0 (2020).|||Oncken, C. A., Litt, M. D., McLaughlin, L. D. & Burki, N. A. Nicotine concentrations with electronic cigarette use: effects of sex and flavor. Nicotine Tob. Res.17 (4), 473–478 (2015).|||Polosa, R. et al. Health impact of E-cigarettes: a prospective 3.5-year study of regular daily users who have never smoked. Sci. Rep.7 (1), 13825 (2017).|||Shi, H. et al. The effect of electronic-cigarette vaping on cardiac function and angiogenesis in mice. Sci. Rep.9 (1), 4085 (2019).|||OlfertIM et al. Chronic exposure to electronic cigarettes results in impaired cardiovascular function in mice. J. Appl. Physiol. (1985). 124 (3), 573–582 (2018).|||El-Mahdy, M. A. et al. Long-term electronic cigarette exposure induces cardiovascular dysfunction similar to tobacco cigarettes: role of nicotine and exposure duration. Am. J. Physiol. Heart Circ. Physiol.320 (5), H2112–H2129 (2021).|||Alam, F. & Silveyra, P. Sex differences in E-Cigarette Use and Related Health effects. Int. J. Environ. Res. Public. Health. 20 (22), 7079 (2023).|||Hering, D. et al. Heightened acute circulatory responses to smoking in women. Blood Press.17 (3), 141–146 (2008).|||Kotlyar, M., Thuras, P., Hatsukami, D. K. & al’Absi, M. Sex differences in physiological response to the combination of stress and smoking. Int. J. Psychophysiol.118, 27–31 (2017).|||Dai, W. et al. Effects of electronic cigarette vaping on Cardiac and vascular function, and post-myocardial infarction remodeling in rats. Cardiovasc. Toxicol.24 (2), 199–208 (2024).|||Rahman, A., Alqaisi, S., Alzakhari, R. & Saith, S. Characterization and summarization of the impact of electronic cigarettes on the Cardiovascular System: a systematic review and Meta-analysis. Cureus15 (5), e39528 (2023).|||Kleinman, M. T. et al. E-cigarette or Vaping Product Use-Associated Lung Injury Produced in an animal model from electronic cigarette vapor exposure without tetrahydrocannabinol or vitamin E oil. J. Am. Heart Assoc.9 (18), e017368 (2020).|||Alavi, R. et al. Adverse Cardiovascular effects of Nicotine delivered by Chronic Electronic cigarettes or Standard cigarettes captured by Cardiovascular intrinsic frequencies. J. Am. Heart Assoc.13 (18), e035462 (2024).