Quick Links

Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myoc

Authors: J Leor|||M Patterson|||M J Quinones|||L H Kedes|||R A Kloner

Journal: Circulation

Publication Type: Journal Article

Date: 1996

ID: 8901770

Affiliations:

Affiliations

    Heart Institute, University of Southern California, Los Angeles, USA.||||||||||||

Abstract

Unlike skeletal myocytes, mammalian adult cardiomyocytes cannot regenerate after injury. A possible strategy to increase viability and augment ventricular function after myocardial injury is fetal myocardial tissue transplantation. The engrafted fetal cells are a potential source of growth factors and can be used for cardiomyocyte-based gene therapy. The purpose of our study was to test the feasibility and efficiency of fetal cardiomyocyte transplantation into a model of myocardial infarction.


Chemical List

    Actins