Cardiovascular Research

Is calcium a mediator of infarct size reduction with preconditioning in canine myocardium?

Authors: K Przyklenk|||K Hata|||R A Kloner

Affiliations: + Expand

Abstract

The cellular mechanisms by which brief episodes of ischemia protect or "precondition" the heart and limit infarct size caused by a later period of sustained coronary artery occlusion remain unresolved. We propose that calcium may be an important mediator in eliciting this cardioprotection.

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Chemical List

5-dimethylamiloride|||Amiloride|||Calcium Chloride|||Calcium