Migraine and Cognition and Brain Integration Lab, Xianghong Arakaki

Alpha rhythm and Alzheimer's disease: Has Hans Berger's dream come true?

Authors: Claudio Babiloni|||Xianghong Arakaki|||Sandra Baez|||Robert J Barry|||Alberto Benussi|||Katarzyna Blinowska|||Laura Bonanni|||Barbara Borroni|||Jorge Bosch Bayard|||Giuseppe Bruno|||Alessia Cacciotti|||Filippo Carducci|||John Carino|||Matteo Carpi|||Antonella Conte|||Josephine Cruzat|||Fabrizia D'Antonio|||Stefania Della Penna|||Claudio Del Percio|||Pierfilippo De Sanctis|||Javier Escudero|||Giovanni Fabbrini|||Francesca R Farina|||Francisco J Fraga|||Peter Fuhr|||Ute Gschwandtner|||Bahar Güntekin|||Yi Guo|||Mihaly Hajos|||Mark Hallett|||Harald Hampel|||Lutfu Hanoğlu|||Ira Haraldsen|||Mahmoud Hassan|||Christoffer Hatlestad-Hall|||András Attila Horváth|||Agustin Ibanez|||Francesco Infarinato|||Alberto Jaramillo-Jimenez|||Jaeseung Jeong|||Yang Jiang|||Maciej Kamiński|||Giacomo Koch|||Sanjeev Kumar|||Giorgio Leodori|||Gang Li|||Roberta Lizio|||Susanna Lopez|||Raffaele Ferri|||Fernando Maestú|||Camillo Marra|||Laura Marzetti|||William McGeown|||Francesca Miraglia|||Sebastian Moguilner|||Davide V Moretti|||Faisal Mushtaq|||Giuseppe Noce|||Lorenzo Nucci|||John Ochoa|||Paolo Onorati|||Alessandro Padovani|||Chiara Pappalettera|||Mario Alfredo Parra|||Matteo Pardini|||Roberto Pascual-Marqui|||Walter Paulus|||Vittorio Pizzella|||Pavel Prado|||Géraldine Rauchs|||Petra Ritter|||Marco Salvatore|||Hernando Santamaria-García|||Michael Schirner|||Andrea Soricelli|||John-Paul Taylor|||Hatice Tankisi|||Franca Tecchio|||Stefan Teipel|||Alpha Tom Kodamullil|||Antonio Ivano Triggiani|||Mitchell Valdes-Sosa|||Pedro Valdes-Sosa|||Fabrizio Vecchio|||Keith Vossel|||Dezhong Yao|||Görsev Yener|||Ulf Ziemann|||Anita Kamondi

Date: 2025

PMID: 39978053

Perifoveal Choriocapillaris Flow Deficits Associated With Cerebrospinal Fluid Aβ42/tau in Presymptomatic Alzheimer's Disease.

Authors: Jane W Chan|||Giulia Corradetti|||Xiaomeng Wu|||Natalie Astraea|||Xianghong Arakaki|||Alfred N Fonteh|||Astrid M Suchy-Dicey|||SriniVas Sadda

Date: 2025

PMID: 40434374

RNA-seq reveals transcriptomic differences in circadian-related genes of the choroid plexus in a preclinical chronic migraine mo

Authors: Yohannes W Woldeamanuel|||Chenchen Xia|||Sam Ding|||Alfred Fonteh|||Xianghong Arakaki

Date: 2025

PMID: 40501738

Selective vulnerability of GABAergic neurons in chronic migraine.

Authors: Kazi Helal Hossain|||Timothy Chuong|||Emily Abad|||Justin Lin|||Chenchen Xia|||Meng Li|||Yibu Chen|||Xianghong Arakaki|||Anju Vasudevan

Date: 2025

PMID: 41266979

Higher sodium in older individuals or after stroke/reperfusion, but not in migraine or Alzheimer's disease - a study in differen

Authors: Chenchen Xia|||Wangde Dai|||Juan Carreno|||Andrea Rogando|||Xiaomeng Wu|||Darren Simmons|||Natalie Astraea|||Nathan F Dalleska|||Alfred N Fonteh|||Anju Vasudevan|||Xianghong Arakaki|||Robert A Kloner

Date: 2024

PMID: 39284837

Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia.

Authors: Yang Jiang|||Jennifer Neal|||Pradoldej Sompol|||Görsev Yener|||Xianghong Arakaki|||Christopher M Norris|||Francesca R Farina|||Agustin Ibanez|||Susanna Lopez|||Abdulhakim Al-Ezzi|||Voyko Kavcic|||Bahar Güntekin|||Claudio Babiloni|||Mihály Hajós

Date: 2024

PMID: 39206795

Disrupted brain functional connectivity as early signature in cognitively healthy individuals with pathological CSF amyloid/tau.

Authors: Abdulhakim Al-Ezzi|||Rebecca J Arechavala|||Ryan Butler|||Anne Nolty|||Jimmy J Kang|||Shinsuke Shimojo|||Daw-An Wu|||Alfred N Fonteh|||Michael T Kleinman|||Robert A Kloner|||Xianghong Arakaki

Date: 2024

PMID: 39179782

Associations of Plasma Glutamatergic Metabolites with Alpha Desynchronization during Cognitive Interference and Working Memory T

Authors: Vincent Sonny Leong|||Jiaquan Yu|||Katherine Castor|||Abdulhakim Al-Ezzi|||Xianghong Arakaki|||Alfred Nji Fonteh

Date: 2024

PMID: 38891102

Choriocapillaris and Retinal Vascular Alterations in Presymptomatic Alzheimer's Disease.

Authors: Giulia Corradetti|||Deniz Oncel|||Shin Kadomoto|||Xianghong Arakaki|||Robert A Kloner|||Alfredo A Sadun|||SriniVas R Sadda|||Jane W Chan

Date: 2024

PMID: 38294804

Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer's dis

Authors: Shao-Min Hung|||Sara W Adams|||Cathleen Molloy|||Daw-An Wu|||Shinsuke Shimojo|||Xianghong Arakaki

Date: 2024

PMID: 37817004

Resting heart rate (variability) and cognition relationships reveal cognitively healthy individuals with pathological amyloid/ta

Authors: Cathleen Molloy|||Elizabeth H Choy|||Rebecca J Arechavala|||David Buennagel|||Anne Nolty|||Mitchell R Spezzaferri|||Caleb Sin|||Shant Rising|||Jeremy Yu|||Abdulhakim Al-Ezzi|||Michael T Kleinman|||Robert A Kloner|||Xianghong Arakaki

Date: 2023

PMID: 37587981

Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer's dis

Authors: Shao-Min Hung|||Sara W Adams|||Cathleen Molloy|||Daw-An Wu|||Shinsuke Shimojo|||Xianghong Arakaki

Date: 2023

PMID: 37292951

The connection between heart rate variability (HRV), neurological health, and cognition: A literature review.

Authors: Xianghong Arakaki|||Rebecca J Arechavala|||Elizabeth H Choy|||Jayveeritz Bautista|||Bishop Bliss|||Cathleen Molloy|||Daw-An Wu|||Shinsuke Shimojo|||Yang Jiang|||Michael T Kleinman|||Robert A Kloner

Date: 2023

PMID: 36937689

Stronger implicit interference in cognitively healthy older participants with higher risk of Alzheimer's disease.

Authors: Shao-Min Hung|||Daw-An Wu|||Shinsuke Shimojo|||Xianghong Arakaki

Date: 2022

PMID: 36187196

Alpha desynchronization during Stroop test unmasks cognitively healthy individuals with abnormal CSF Amyloid/Tau.

Authors: Xianghong Arakaki|||Shao-Min Hung|||Roger Rochart|||Alfred N Fonteh|||Michael G Harrington

Date: 2022

PMID: 35066324

Are there consistent abnormalities in event-related EEG oscillations in patients with Alzheimer's disease compared to other dise

Authors: Bahar Güntekin|||Tuba Aktürk|||Xianghong Arakaki|||Laura Bonanni|||Claudio Del Percio|||Rebecca Edelmayer|||Francesca Farina|||Raffaele Ferri|||Lütfü Hanoğlu|||Sanjeev Kumar|||Roberta Lizio|||Susanna Lopez|||Brian Murphy|||Giuseppe Noce|||Fiona Randall|||Alexander T Sack|||Fabrizio Stocchi|||Görsev Yener|||Ebru Yıldırım|||Claudio Babiloni

Date: 2022

PMID: 34460957

Plasma Lipolysis and Changes in Plasma and Cerebrospinal Fluid Signaling Lipids Reveal Abnormal Lipid Metabolism in Chronic Migr

Authors: Katherine Castor|||Jessica Dawlaty|||Xianghong Arakaki|||Noah Gross|||Yohannes W Woldeamanuel|||Michael G Harrington|||Robert P Cowan|||Alfred N Fonteh

Date: 2021

PMID: 34531722

Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel.

Authors: Claudio Babiloni|||Xianghong Arakaki|||Hamed Azami|||Karim Bennys|||Katarzyna Blinowska|||Laura Bonanni|||Ana Bujan|||Maria C Carrillo|||Andrzej Cichocki|||Jaisalmer de Frutos-Lucas|||Claudio Del Percio|||Bruno Dubois|||Rebecca Edelmayer|||Gary Egan|||Stephane Epelbaum|||Javier Escudero|||Alan Evans|||Francesca Farina|||Keith Fargo|||Alberto Fernández|||Raffaele Ferri|||Giovanni Frisoni|||Harald Hampel|||Michael G Harrington|||Vesna Jelic|||Jaeseung Jeong|||Yang Jiang|||Maciej Kaminski|||Voyko Kavcic|||Kerry Kilborn|||Sanjeev Kumar|||Alice Lam|||Lew Lim|||Roberta Lizio|||David Lopez|||Susanna Lopez|||Brendan Lucey|||Fernando Maestú|||William J McGeown|||Ian McKeith|||Davide Vito Moretti|||Flavio Nobili|||Giuseppe Noce|||John Olichney|||Marco Onofrj|||Ricardo Osorio|||Mario Parra-Rodriguez|||Tarek Rajji|||Petra Ritter|||Andrea Soricelli|||Fabrizio Stocchi|||Ioannis Tarnanas|||John Paul Taylor|||Stefan Teipel|||Federico Tucci|||Mitchell Valdes-Sosa|||Pedro Valdes-Sosa|||Marco Weiergräber|||Gorsev Yener|||Bahar Guntekin

Date: 2021

PMID: 33860614

EEG measures for clinical research in major vascular cognitive impairment: recommendations by an expert panel.

Authors: Claudio Babiloni|||Xianghong Arakaki|||Laura Bonanni|||Ana Bujan|||Maria C Carrillo|||Claudio Del Percio|||Rebecca M Edelmayer|||Gary Egan|||Fanny M Elahh|||Alan Evans|||Raffaele Ferri|||Giovanni B Frisoni|||Bahar Güntekin|||Atticus Hainsworth|||Harald Hampel|||Vesna Jelic|||Jaeseung Jeong|||Doh Kwan Kim|||Milica Kramberger|||Sanjeev Kumar|||Roberta Lizio|||Flavio Nobili|||Giuseppe Noce|||Aina Puce|||Petra Ritter|||Dirk J A Smit|||Andrea Soricelli|||Stefan Teipel|||Federico Tucci|||Perminder Sachdev|||Mitchell Valdes-Sosa|||Pedro Valdes-Sosa|||Andrea Vergallo|||Görsev Yener

Date: 2021

PMID: 33845399

Evidence that blood-CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with

Authors: Robert P Cowan|||Noah B Gross|||Melanie D Sweeney|||Abhay P Sagare|||Axel Montagne|||Xianghong Arakaki|||Alfred N Fonteh|||Berislav V Zlokovic|||Janice M Pogoda|||Michael G Harrington

Date: 2021

PMID: 33724462

Task switching reveals abnormal brain-heart electrophysiological signatures in cognitively healthy individuals with abnormal CSF

Authors: Rebecca Johnson Arechavala|||Roger Rochart|||Robert A Kloner|||Anqi Liu|||Daw-An Wu|||Shao-Min Hung|||Shinsuke Shimojo|||Alfred N Fonteh|||Michael T Kleinman|||Michael G Harrington|||Xianghong Arakaki

Date: 2021

PMID: 34666107

Accumulation of Cerebrospinal Fluid Glycerophospholipids and Sphingolipids in Cognitively Healthy Participants With Alzheimer's

Authors: Alfred N Fonteh|||Abby J Chiang|||Xianghong Arakaki|||Sarah P Edminster|||Michael G Harrington

Date: 2020

PMID: 33390893

Compromised Behavior and Gamma Power During Working Memory in Cognitively Healthy Individuals With Abnormal CSF Amyloid/Tau.

Authors: Roger Rochart|||Quanying Liu|||Alfred N Fonteh|||Michael G Harrington|||Xianghong Arakaki

Date: 2020

PMID: 33192465

Correction: Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline.

Authors: Samuel Asanad|||Michele Fantini|||William Sultan|||Marco Nassisi|||Christian M Felix|||Jessica Wu|||Rustum Karanjia|||Fred N Ross-Cisneros|||Abhay P Sagare|||Berislav V Zlokovic|||Helena C Chui|||Janice M Pogoda|||Xianghong Arakaki|||Alfred N Fonteh|||Alfredo A Sadun|||Michael G Harrington

Date: 2020

PMID: 32663228

Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline.

Authors: Samuel Asanad|||Michele Fantini|||William Sultan|||Marco Nassisi|||Christian M Felix|||Jessica Wu|||Rustum Karanjia|||Fred N Ross-Cisneros|||Abhay P Sagare|||Berislav V Zlokovic|||Helena C Chui|||Janice M Pogoda|||Xianghong Arakaki|||Alfred N Fonteh|||Alfredo A Sadun|||Michael G Harrington

Date: 2020

PMID: 32469871

Polyunsaturated Fatty Acid Composition of Cerebrospinal Fluid Fractions Shows Their Contribution to Cognitive Resilience of a Pr

Authors: Alfred N Fonteh|||Matthew Cipolla|||Abby J Chiang|||Sarah P Edminster|||Xianghong Arakaki|||Michael G Harrington

Date: 2020

PMID: 32116789

Lipid Metabolism in Late-Onset Alzheimer's Disease Differs from Patients Presenting with Other Dementia Phenotypes.

Authors: Syena Sarrafpour|||Cora Ormseth|||Abby Chiang|||Xianghong Arakaki|||Michael Harrington|||Alfred Fonteh

Date: 2019

PMID: 31195602

Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation.

Authors: Noah B Gross|||Nastaren Abad|||David Lichtstein|||Shiri Taron|||Lorena Aparicio|||Alfred N Fonteh|||Xianghong Arakaki|||Robert P Cowan|||Samuel C Grant|||Michael G Harrington

Date: 2019

PMID: 31173612

Alpha desynchronization during simple working memory unmasks pathological aging in cognitively healthy individuals.

Authors: Xianghong Arakaki|||Ryan Lee|||Kevin S King|||Alfred N Fonteh|||Michael G Harrington

Date: 2019

PMID: 30601822

Source Connectivity Analysis Can Assess Recovery of Acute Mild Traumatic Brain Injury Patients.

Authors: Lianyang Li|||Xianghong Arakaki|||Michael Harrington|||George Zouridakis

Date: 2018

PMID: 30441066

Alpha desynchronization/synchronization during working memory testing is compromised in acute mild traumatic brain injury (mTBI)

Authors: Xianghong Arakaki|||Michael Shoga|||Lianyang Li|||George Zouridakis|||Thao Tran|||Alfred N Fonteh|||Jessica Dawlaty|||Robert Goldweber|||Janice M Pogoda|||Michael G Harrington

Date: 2018

PMID: 29444081

Brain activation profiles in mTBI: evidence from ERP activity of working memory response.

Authors: Lianyang Li|||Xianghong Arakaki||| Thao Tran|||Michael Harrington|||Nikhil Padhye|||George Zouridakis

Date: 2016

PMID: 28268689

Severe Headache or Migraine History is Inversely Correlated With Dietary Sodium Intake: NHANES 1999-2004.

Authors: Janice M Pogoda|||Noah B Gross|||Xianghong Arakaki|||Alfred N Fonteh|||Robert P Cowan|||Michael G Harrington

Date: 2016

PMID: 27016121

Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999-2004: A Response.

Authors: Janice M Pogoda|||Noah B Gross|||Xianghong Arakaki|||Alfred N Fonteh|||Robert P Cowan|||Michael G Harrington

Date: 2016

PMID: 27432628

Brain activation profiles in mTBI: Evidence from combined resting-state EEG and MEG activity.

Authors: Lianyang Li|||Mattia F Pagnotta|||Xianghong Arakaki|||Thao Tran|||David Strickland|||Michael Harrington|||George Zouridakis

Date: 2015

PMID: 26737894

Sphingolipid metabolism correlates with cerebrospinal fluid Beta amyloid levels in Alzheimer's disease.

Authors: Alfred N Fonteh|||Cora Ormseth|||Jiarong Chiang|||Matthew Cipolla|||Xianghong Arakaki|||Michael G Harrington

Date: 2015

PMID: 25938590

Human cerebrospinal fluid fatty acid levels differ between supernatant fluid and brain-derived nanoparticle fractions, and are a

Authors: Alfred N Fonteh|||Matthew Cipolla|||Jiarong Chiang|||Xianghong Arakaki|||Michael G Harrington

Date: 2014

PMID: 24956173

Altered brainstem auditory evoked potentials in a rat central sensitization model are similar to those in migraine.

Authors: Xianghong Arakaki|||Gary Galbraith|||Victor Pikov|||Alfred N Fonteh|||Michael G Harrington

Date: 2014

PMID: 24680742

Executive function changes before memory in preclinical Alzheimer's pathology: a prospective, cross-sectional, case control stud

Authors: Michael G Harrington|||Jiarong Chiang|||Janice M Pogoda|||Megan Gomez|||Kris Thomas|||Sarah Deboard Marion|||Karen J Miller|||Prabha Siddarth|||Xinyao Yi|||Feimeng Zhou|||Sherri Lee|||Xianghong Arakaki|||Robert P Cowan|||Thao Tran|||Cherise Charleswell|||Brian D Ross|||Alfred N Fonteh

Date: 2013

PMID: 24260210

Alterations in cerebrospinal fluid glycerophospholipids and phospholipase A2 activity in Alzheimer's disease.

Authors: Alfred N Fonteh|||Jiarong Chiang|||Matthew Cipolla|||Jack Hale|||Fatimatou Diallo|||Alejandra Chirino|||Xianghong Arakaki|||Michael G Harrington

Date: 2013

PMID: 23868911

Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat.

Authors: Xianghong Arakaki|||Paige McCleary|||Matthew Techy|||Jiarong Chiang|||Linus Kuo|||Alfred N Fonteh|||Brian Armstrong|||Dan Levy|||Michael G Harrington

Date: 2013

PMID: 23497725

Sodium MRI in a rat migraine model and a NEURON simulation study support a role for sodium in migraine.

Authors: Michael G Harrington|||Eduard Y Chekmenev|||Victor Schepkin|||Alfred N Fonteh|||Xianghong Arakaki

Date: 2011

PMID: 21816771

Extracellular sodium modulates the excitability of cultured hippocampal pyramidal cells.

Authors: Xianghong Arakaki|||Hailey Foster|||Lei Su|||Huy Do|||Andrew J Wain|||Alfred N Fonteh|||Feimeng Zhou|||Michael G Harrington

Date: 2011

PMID: 21679932

Modulation of neuronal activity and plasma membrane properties with low-power millimeter waves in organotypic cortical slices.

Authors: Victor Pikov|||Xianghong Arakaki|||Michael Harrington|||Scott E Fraser|||Peter H Siegel

Date: 2010

PMID: 20644247

Capillary endothelial Na(+), K(+), ATPase transporter homeostasis and a new theory for migraine pathophysiology.

Authors: Michael G Harrington|||Alfred N Fonteh|||Xianghong Arakaki|||Robert P Cowan|||Laurel E Ecke|||Hailey Foster|||Andreas F Hühmer|||Roger G Biringer

Date: 2010

PMID: 19845787

Cardiovascular Research

Migraine and Cognition and Brain Integration Lab

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